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18.03.2022

Getting enough vitamin B6 will make you live longer

If there is an adequate amount of vitamin B6 circulating in your body, you may live longer than if this amount is small. This is what Chinese epidemiologists conclude on the basis of data collected in USA.

Study
Epidemiologists from Wuhan University used data collected in the United States in the National Health and Nutrition Examination Survey. In this project, researchers of 12,190 adults had determined, among other things, the vitamin B6 status of the study participants between 2005 and 2010.

The researchers also collected a variety of other data about the study participants using questionnaires.

The researchers classified the study participants with 30 nanomoles of pyridoxal-5-phosphate [PLP] per liter of blood or more as vitamin B6 sufficient. PLP is the active form of vitamin B6. 70.6 percent of the study participants were in this category.

Vitamin B6 is mainly attached to proteins in the diet. If you eat protein-rich products, you also get vitamin B6. Chicken is an excellent source. An ounce of chicken contains more than 4 milligrams of vitamin B6. According to European guidelines, adults need anywhere from 1.5 to 1.9 milligrams of vitamin B6 per day. Some scientists consider these recommendations to be sub-optimal, but we'll talk about that another time.

In the body, vitamin B6 is involved in almost all major reactions where cells cut and paste with amino acids. Whether it's the biosynthesis of neurotransmitters, amino acids, vitamins or heme, vitamin B6 plays a significant role.

Results
Of the 12,910 study participants, 1,244 died over a period of 5-10 years. After the researchers had brushed out all possible other factors, the chance that someone categorized as vitamin B6 insufficient or vitamin B6 deficient was 17 and 39 percent greater than than someone died with enough PLP in the blood.

Click on the table below for a larger version.

Conclusion
"This study revealed that as a categorized variable, vitamin B6 was inversely associated with all-cause mortality after multivariate adjustment, including sociodemographic factors and lifestyle factors", summarize the researchers.

"These findings suggest that maintaining a sufficient level of serum vitamin B6 may lower the all-cause mortality risk in the general population."

Source:
Nutrients. 2021 Aug 27;13(9):2977.

More:
A high intake of vitamin B6 protects against pancreatic cancer 08.11.2021
Vitamin B6 helps over 60s stay mentally fit 31.03.2017
Vitamin B6 protects against Parkinson's 13.11.2015

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