Q10 makes type-2 diabetics healthier
Supplementation with Q10 lowers the glucose level in people with type-2 diabetes. In addition, Q10 increases the concentration of the 'good cholesterol' HDL, which reduces the risk of cardiovascular disease. Chinese researchers, associated with Hunan University of Chinese Medicine, come to this conclusion in a meta-study in the International Journal of Endocrinology.
The researchers collected 13 trials in which people with diabetes type-2, who were treated with diabetes medication, also received Q10. A total of 765 subjects participated in the trials. The Chinese aggregated the data and re-analyzed them.
Administration of Q10 reduced the concentration of glycosylated hemoglobin [HbA1c] in the blood of the subjects. Glycosylated hemoglobin is a marker for the exposure to glucose in the longer term: the lower the concentration of glycosylated hemoglobin, the lower the glucose level has been over the past weeks or months.
Click on the figures below for a larger version.
Q10 also reduced fasting glucose levels. This effect, and the reduction of the glycosylated hemoglobin concentration, show that Q10 supplementation helps control glucose levels. There was a trend that Q10 reduced insulin resistance, but this was not statistically significant.
Supplementation with Q10 finally increased HDL levels. Also nice.
"Coenzyme Q10 may assist glycemic control [...] and improve HDL-C in patients with type-2 diabetes mellitus", summarize the reserachers. "However, the limitations in randomized controlled trials, including small sample sizes and short duration, make the result to be interpreted cautiously."
"The benefits from long-term treatment of coenzyme Q10 beyond 6 months remain to be defined by future studies. Meanwhile, more randomized, double-blind, large-sample-size trials of coenzyme Q10 for type-2 diabetes mellitus are needed in the future to validate or revise the result of this work."
Int J Endocrinol. 2018 Sep 16;2018:6484839.
Q10 makes cells more sensitive to insulin 15.02.2018
Insulin & Glucose Metabolism