L-Arginine | A reduction in blood pressure for everyone
L-arginine supplementation lowers blood pressure. For an ordinary supplement that you can buy in any vitamin shop, the effect is surprisingly large. In addition, according to a meta-study from 2022, the supplement should be effective in practically everyone.
Researchers from the nutrition group of Tehran University of Medical Sciences in Iran collected 22 previously published trials in the scientific literature in which subjects had been given L-arginine supplements and the effect on blood pressure was then recorded. The researchers aggregated the results of the trials and analyzed them again.
L-arginine supplementation reduced systolic and diastolic blood pressure by 6.4 and 2.6 points, respectively. That is what the figures below tell you. Click on them for a larger version.
Previously published meta-studies also concluded that L-arginine supplementation lowers blood pressure. What this meta-study adds to these is the confirmation that L-arginine seems to work in all categories of humans. Whether your blood pressure is high or low, whether you are healthy or unhealthy, whether you have a high BMI or not, arginine supplementation will lower your blood pressure.
The duration of the trial was not a major factor in the effectiveness, the dosage was. You have to use 4 grams of arginine per day or more to see an effect. At doses of more than 9 grams per day, arginine's antihypertensive effect disappeared.
Adv Nutr. 2022 Aug 1;13(4):1226-42.
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