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29.10.2022


This dose of thiamine increases your glucose uptake

A daily hefty dose of thiamine allows the body to absorb more glucose from the blood. According to a human study in the European Journal of Nutrition, supplementation with thiamine makes type-2 diabetics healthier. Is thiamine in high doses also interesting for athletes who consume a lot of carbohydrates?


This dose of thiamine increases your glucose uptake


Study
Australian diabetologists at Curtin University experimented with 12 people aged 18-75 with type 2 diabetes. On one occasion they gave the subjects a placebo every day for 6 weeks, on the other occasion the subjects were given a capsule containing 100 milligrams of thiamine HCl 3 times a day for 6 weeks.

The subjects therefore took 300 milligrams of thiamine HCl per day. The subjects took the capsules with their meals.

The subjects were allowed to eat as many carbohydrates as they wanted.

Results
Thiamine supplementation reduced the concentration of glucose in the blood of the subjects over a 24-hour period by 11 percent. The vitamin had no effect on insulin levels.


This dose of thiamine increases your glucose uptake


This dose of thiamine increases your glucose uptake


Thiamine supplementation had no effect on kidney function [eGFR], the table above shows. Click it for a larger version.

Insulin resistance in the placebo group increased, but remained stable in the thiamine group.

Conclusion
"Thiamine supplementation may improve glucose tolerance in individuals with hyperglycemia at early stages and may have a role in the prevention or delay of type-2 diabetes in patients with impaired glucose regulation", write the researchers.

"Further studies are required to confirm these results and investigate the mechanisms of these effects."

Source:
Eur J Nutr. 2013 Oct;52(7):1821-4.

More:
Fursultiamine makes physical exercise less tiring 09.06.2016
High-thiamine diet reduces chance of depression 08.03.2014
50 mg vitamin B1 supplement improves your mood and speeds up your reactions 02.03.2014

Archives:
Insulin & Glucose Metabolism
Vitamin B
Vitamins


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