Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
Surviving covid thanks to GABA supplementation
GABA supplementation may not only improve sleep quality and reduce stress, but may also protect against the deadly effects of a coronavirus infection. That is what an American animal study suggests.
GABA inhibits inflammation. The researchers have been studying the anti-inflammatory effect of GABA for years. They previously showed that GABA alleviates diabetes by inhibiting inflammation.
After being infected with the coronavirus, half of the mice were given drinking water in which the researchers had added GABA. If the mice had been adult humans, they would have received about 2,400 milligrams of GABA daily. This is a somewhat high, but certainly not astronomically high dose.
In some of the mice in this group, supplementation started on the day of infection [GABA0]. In another part this only happened 3 days after the infection [GABA3].
The other half of the mice received drinking water without additives.
GABA is a neurotransmitter that interacts with different types of GABA receptors. A much more specific GABA receptor agonist is baclofen. Baclofen has particular affinity for the GABA-B receptor.
There is also such a thing as a GABA-A receptor. A substance that specifically acts on this receptor is homotaurine.
Because the researchers wanted to know which receptor for inhibiting inflammatory reactions during a serious corona infection is now most relevant, they repeated their tests with those two substances. Homotaurine appeared to protect the mice against disease and death, baclofen did not.
So it is stimulation of the GABA-A receptor that may protect against covid.
By the way, if the mice had been adult humans, they would have ingested about 300 milligrams of homotaurine daily.