Better vitamin uptake from supplements with Ester-C than from supplements with regular vitamin C
Ester C is eight times more expensive per mg than ordinary vitamin C, but also works considerably better than the regular variety. That's the message in the results of a human study published in SpringerPlus.
The researchers gave 36 participants 1000 mg vitamin C on two separate occasions. On one occasion the participants got regular vitamin C; on the other they got Ester-C. Ester C is the calcium salt of vitamin C. The researchers then monitored the participants for 24 hours.
The study was financed by the supplements brand NBTY, which markets Ester-C. The researchers also worked for the company.
Supplementation with Ester-C increased the vitamin C concentration in the participants’ blood in much the same way as supplementation with regular vitamin C did.
When the researchers measured the concentration of vitamin C in the participants' blood cells, they observed that supplementation with Ester-C resulted in a bigger rise than supplementation with regular vitamin C did.
"In conclusion, Ester-C significantly increased leukocyte vitamin C levels compared to ascorbic acid," the researchers summarised. "This may be due to Ester-C's metabolites, which have been shown to facilitate absorption and enhance retention."
"The superior bioavailability of Ester-C in leukocytes may be beneficial to overall immune function since intracellular vitamin C levels are vital to the fundamental process of leukocytes. More studies are needed to better understand how Ester-C is associated with disease prevention and treatment."
Springerplus. 2016 Jul 25;5(1):1161.
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