ergo-log.com

Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "

08.01.2023

Shilajit induces muscle collagen biosynthesis

Supplementation with shilajit induces the activity of genes in muscle tissue which direct muscle cells to produce non-contractile extracellular proteins, according to a human study published in 2016 in the Journal of Medicinal Food.

Study
Researchers at Ohio State University gave 16 obese subjects aged 21-70 a capsule containing 250 milligrams of shilajit twice a day for 12 weeks. During the last 4 weeks of the study, the subjects ran 3 times a week for 20 minutes on a treadmill at an intensity of 70 percent of their maximal oxygen uptake.

The supplement in question was PrimaVie, a Natreon product. [natreoninc.com] Natreon sponsored the study.

Just before the supplementation period started, after week 8 and after week 12, the researchers removed some muscle tissue from the test subjects and determined the activity of a number of genes involved in the biosynthesis of muscle tissue.

Results
Shilajit supplementation increased the activity of genes encoding muscle collagens. This effect may be greatly increased in combination with frequent exercise. We are not entirely sure, because the researchers did not have a control group that only ran and did not use shilajit.

Wild speculation
Shilajit supplementation activated genes in muscle tissue that force muscles to produce more collagens. These proteins form the extracellular structures of the muscles. If you compare muscles to a car, the chassis consists of these non-contractile proteins. The motor consists of contractile proteins.

Collagens mainly consist of non-essential amino acids such as proline, hydroxyproline, glycine and arginine, while the contractile proteins of muscles consist of essential amino acids.

The body must obtain essential amino acids from food. Although non-essential amino acids are also found in food, the body can also produce them by converting essential amino acids.

According to a sponsored study in which people in their seventies who trained with weights were given collagens, supplementing with collagen promotes muscle growth, at least in this group. [More] We should immediately notice that the muscle-building effect of whey exceeds that of collagen.

What would supplementing with both shilajit and collagen do to muscle building?

Source:
J Med Food. 2016 Jul;19(7):701-9.

More:
A capsule of shilajit a day makes bones stronger 25.12.2022
Only strong athletes get stronger through shilajit supplementation 19.11.2022

Archives:
Unusual Muscle Building Strategies
Shilajit

Pinoresinol and vanillic acid | Phytochemicals that mimic the anabolic effect of IGF-1 Supplements containing vanillic acid and pinoresinol, two compounds found in several plants, may help boost muscle growth.	Paraxanthine makes you stronger, more muscular and increases your stamina | Animal study In addition, paraxanthine supplementation may improve cardiovascular health.	Anabolic effect of dileucine greater than that of leucine Martin Purpura and Jäger of research firm Increnovo discovered that the dipeptide of leucine stimulates muscle protein synthesis more strongly than regular leucine.