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Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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28.03.2020 |
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Combination of S-adenosylmethione and betaine combats mild depression
Study 1
The researchers gave half of their subjects a supplement every day for 3 months with 800 milligrams of S-adenosylmethionine [divided into 2 doses per day], and the other half every day 750 milligrams of S-adenosylmethionine plus 375 milligrams of betaine per day [divided between 3 doses per day].
During the 90 days that the experiment lasted, the subjects who combined S-adenosylmethione with their antidepressants showed progress. The classic symptoms of depression, such as anxiety and unrest, decreased, while the subjects' estimate of their physical health increased.
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"On the basis of study results, it may be assumed that the administration of S-adenosylmethionine plus betaine is a better adjunctive therapy than the administration of S-adenosylmethionine alone in subjects with mild-to-moderate depression who are low responders to conventional antidepressive drugs", write the Italians.
Study 2
After 6-12 months, the number of people with relatively high depression scores in the supplementation group had decreased by 50-64 percent. In the amitriptyline group, this was only 13-4 percent.
Click on the figure below for a larger version.
Side effects were significantly less common among supplement users than amitriptyline users.
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