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21.09.2012


Wheat bran has anti-oestrogenic effect in humans too

Yesterday we wrote that high-fibre wheat bran supplementation helped estradiol to be eliminated faster out of rats' bodies. Human studies from the 1990s confirm that wheat fibres can reduce estradiol levels wheat bran reduces them by ten to twenty percent.

In 1997 a Kellogg sponsored study was published in Nutrition, in which pre-menopausal women were given 5, 10 or 20 g of wheat bran daily for two months. The supplement that the researchers used was All Bran, manufactured by the sponsor. The 10 g dose lowered the oestrogen level the most, the researchers discovered.

The researchers took into the women's menstrual cycle and examined separately the effect of fibre supplementation during the follicular [table immediately below] and luteal [second table below] phases. During the follicular phase the women's estradiol and oestrone levels decreased by 6 and 19 percent respectively. During the luteal phase the decreases were 26 and 14 percent respectively.

Estradiol levels are higher during the luteal phase than during the follicular phase. And the higher the estradiol level in the blood, the stronger the oestrogenic suction power of wheat bran.


Wheat bran has anti-oestrogenic effect in humans too


Wheat bran has anti-oestrogenic effect in humans too


Six years earlier the same researchers published a comparable study in the American Journal of Nutrition, on the effect of 15 g fibre supplementation on oestrogen levels. This study was also sponsored by the Kellogg Company. [Am J Clin Nutr. 1991 Sep;54(3):520-5.] In this study the researchers compared the effects of fibres from wheat, maize and oats. Only the fibre from wheat lowered oestrogen levels.


Wheat bran has anti-oestrogenic effect in humans too


Wheat bran has anti-oestrogenic effect in humans too


Wheat bran has anti-oestrogenic effect in humans too


Daily supplementation of about 15 g wheat bran lowered estradiol levels by 15 percent.

Source:
Nutrition. 1997 Jun;13(6):535-9.

More:
The anti-oestrogenic effect of wheat bran 20.09.2012