Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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07.02.2015 |
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Trenbolone may increase Alzheimer's risk
Bodybuilders who use the anabolic steroid trenbolone may be increasing their chances of developing Alzheimer's disease, fear molecular scientists Fucui Ma and Daicheng Liu of Shandong Normal University in China. Ma and Liu gave mice injections of trenbolone and saw almost immediate changes in the animals' brains that would give neurologists sleepless nights.
Alzheimer's
Enzymes cut APP up into pieces, and if this process goes as it should your brain cells are doing what they're supposed to. But if the enzymes start to mess up – because of faulty genes or dangerous environmental factors – toxic pieces of protein are formed. The most risky of these is amyloid-beta-42, which accumulates in the brain, forming plaques and ultimately killing brain cells. The brains of people who have died of Alzheimer's contain large amounts of amyloid-beta-42, so most neurologists think that amyloid-beta-42 is the cause of Alzheimer's and related forms of dementia.
Study
Results
The Chinese also did experiments with brain cells that they exposed for 48 hours to 100 nanomol trenbolone [TB]. The addition of anti-androgens such as flutamine [Flu] reduced the amyloid-beta-42 accumulation. So brain damage caused by trenbolone is due to its androgenic effects.
A combination of trenbolone and DHT boosts the accumulation of amyloid-beta-42.
Conclusion
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