Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
Taurine protects steroids users' testes
Steroids users may prevent the decline of their testosterone and sperm production by using taurine. Egyptian pharmacologist Maha Ahmed of Misr University for Science and Technology in Giza suspects this may be the case. Ahmed injected lab animals for two months with nandrolone decanoate and discovered that taurine supplementation drastically reduced the negative endocrinological side effects of this anabolic steroid.
The testes is one type of tissue where you find high levels of taurine. If you boost the taurine concentration in the testes by giving animals supplements, then their testosterone production rises.
By today's standards a dose of 140 mg nandrolone decanoate is not much, even though bodybuilders in the 1960s and 70s would have had a different opinion.
A second group of rats received not only nandrolone decanoate injections but also taurine. Ahmed gave them taurine orally. The human equivalent of the dose would be 1500 mg taurine daily.
Nandrolone decanoate reduced the production of sperm, affected their viability, reduced their motility and increased the chance of abnormal sperm. Taurine noticeably reduced these effects.
Nandrolone decanoate reduced the production of enzymes involved in the biosynthesis of testosterone, such as 3- and 17-beta-HSD, but taurine largely halted this reduction.
Nandrolone decanoate reduced the concentration of glutathione in the testes, but this didn't happen when the rats were given taurine as well.
Nandrolone decanoate caused the testes to produce more inflammatory proteins such as TNF-alpha, but this didn't happen if the lab animals were also given taurine.
Ahmed observed more genetic damage in the rats that had been injected with nandrolone decanoate, but not in those that had also had taurine.
Nandrolone decanoate induced the testes to make more of the suicide enzyme caspase-3, but not... Ok, you get it.
Steroids use forces the cells in the testes to become inactive, and inactive cells destroy themselves. Taurine slowed this process down.
"Clinical trials are strongly recommended to investigate the protective effects of taurine in nandrolone decanoate abusers against associated testicular toxicity and possible infertility."