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This is what happens to your bones if you take 150 mg of resveratrol every day for a year
Resveratrol supplementation may well slow down aging, some scientists suspect. Whether that is really the case is a matter of debate. According to a human study, published in 2020 in the Journal of Bone and Mineral Research, resveratrol at least inhibits skeletal aging.
On another occasion, the women were given a placebo for one year.
Post-menopausal women have an increased risk of osteoporosis. Since resveratrol sabotages the catabolic switch NF-kappaB in cells in fundamental research, the researchers suspected that resveratrol supplementation could stop the breakdown of bone tissue in this group.
During the experiment, the researchers recorded the condition of the bone mass using scans.
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In the blood, resveratrol reduced the concentration of C-terminal telopeptide type-1 collagen [CTX]. CTX is a biomarker for bone breakdown.
Vitamin D and calcium
"Those who took calcium with or without vitamin D had a greater increase in lumbar spine bone mass density than those who took neither", write the Australians. "Factorial analysis confirmed this observation."
"In the crossover comparison, those who took both calcium and vitamin D had a greater resveratrol-induced increase in lumbar spine bone mass density than those taking calcium only. They also had a significantly greater increase in total hip bone mass density and reduction in hip fracture risk than those taking neither calcium nor vitamin D."
The researchers do not provide figures.
Foods or supplements?
According to Spanish measurements, the average resveratrol intake from regular foods is 1 milligram per day.