Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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02.11.2021 |
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OPK-88004 | This SARM increases free testosterone levels
Study
OPK-88004 was developed by the pharmaceutical company Transition Therapeutics. In 2016 OPKO bought Health Transition Therapeutics.
Results
The 15 milligram dose also seemed to improve performance on the stair climber and leg press, but the increase was not statistically significant.
Click on the table below for a larger version.
OPK-88004 did not increase PSA levels. This means that the SARM did not stimulate the growth of any prostate cancer cells present. Remarkably, OPK-88004 lowered the total testosterone level and the estradiol level, but actually increased the free testosterone level.
Click on the table for a larger version.
OPK-88004 also had no prosexual effects. For this reason, and because the effects of the new SARM on strength and physical performance were disappointing, the researchers have their doubts about OPK-88004's market potential.
Conclusion
"OPK-88004 increased lean body mass and decreased fat mass but did not improve sexual symptoms or physical performance."
"The short-term safety data are reassuring and provide the rationale for investigating the efficacy of SARMs, such as the OPK-88004, that were developed for their preferential muscle and bone anabolic effects, among prostate cancer survivors with physical dysfunction, and for developing novel SARMs that preferentially improve sexual function."
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