Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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26.08.2020 |
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Is LGD-4033 liver toxic?
The patient
These are classic symptoms of liver damage. Indeed, when the doctors scanned the bodybuilder's abdominal cavity, they noticed that the man's liver was larger than normal. A biopsy showed that the bodybuilder's liver was scarred in places. The channels that transport bile salts to the intestines were closed.
In the weeks that followed, the doctors monitored four markers of liver damage in the bodybuilder's blood. The figure below shows that the man's liver condition slowly improved.
How is that possible?
The companies that are selling SARMs on line and some bodybuilding gurus recommend significantly higher doses. For example, the doctors' patient took ten times the highest dose tested in the 2013 trial. Perhaps, the doctors speculate, LGD-4033 in those high doses is taxing on the liver.
Some LGD-4033 users have published thier blood work on internet forums. They don't show indications of liver damage.
Maybe the bodybuilder about which this post is about was using a wrong product. Not all SARMs in online stores are carefully produced, according to recent English and American research. [JAMA. 2017 Nov 28;318(20):2004-10.]
Or maybe he was using other substances than just LGD-4033, and not informing his practitioners about it. Or perhaps LGD-4033 can cause liver damage in one person, but not in another.
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