A few grams of galacto-oligosaccharides make your protein shake a better muscle builder
Galacto-oligosaccharides are dietary fibers that should stimulate the immune system of babies. That's why the food industry uses galacto-oligosaccharides mainly in baby food. However, according to a patent from the Dutch company Nutricia, the same galacto-oligosaccharides are also interesting for people who want to maintain or enlarge their muscle mass.
The patent discusses the results of an animal study, in which the researchers injected mice with cancer cells [TB], and then recorded the breakdown of the extensor digitorum longus [EDL] and soleus extensor. This was done by comparing the weight of the muscles with that of mice in a control group without cancer [C].
Some of the cancer mice received feed with galacto-oligosaccharides [TB-Gos]. The researchers used Vivinal, a galacto-oligosaccharide produced by FrieslandCampina, another Dutch company. [vivinalgos.com]
The administration of galacto-oligosaccharides reduced muscle breakdown by roughly thirty percent.
Galacto-oligosaccharides consist of a glucose unit to which 1 to 8 galactose units are attached. You can see the building plan above. The body can not digest galacto-oligosaccharides. They are therefore fibers. And because micro-organisms in the gut can ferment galacto-oligosaccharides and convert them into nutrients that the body can absorb - such as short chain fatty acids - galacto-oligosaccharides are prebiotics as well.
The patent we are discussing now relates to galacto-oligosaccharides that consist of 67-80 percent chains of 3-5 units.
The researchers calculated the human equivalent of the doses they used in their animal studies: 10-65 milligrams per kilogram of body weight per day. For someone of 80 kilos that is 800-5200 milligrams per day.
Combination with other nutrients
The anabolic effect of galacto-oligosaccharides is probably best expressed in combination with other nutrients, the researchers think. With proteins, of course - and in addition with omega-3 fatty acids, slow carbs and other fibers. Here you get an idea of a functional food that might protect muscle mass.
US Patent 9,555,059 B2.
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