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Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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02.04.2012 |
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Tungsten: weight loss trace element
A supplement containing the transition metal tungsten encourages weight loss. Endocrinologists at the University of Barcelona stumbled across the weight-loss effect of tungsten when doing an animal study, which was published in 2005 in Endocrinology.
The Spanish research group discovered in the mid-nineties that tungsten imitates the effect of insulin in rats. [J Biol Chem. 1994 Aug 5; 269(31): 20047-53.] It then became clear from a series of animal studies that tungsten also made rats thinner. In the 2005 study the Spanish researchers re-examined this effect.
The researchers fattened male rats using feed that was enriched with bacon, liver sausage and cookies [UO]. Some of the fattened rats were given drinking water in which tungsten had been dissolved. To be precise: the researchers used Na2WO4, the sodium salt of tungsten [UO, tungstate]. One ml of drinking water contained 0.3, 0.7 or 2 mg of the salt. The rats consumed an average of 33, 77 or 227 mg tungsten per kg bodyweight per day. Don't try this at home, folks.
The rats in the tungsten group put on less weight than the animals that were fattened but not given the supplement. The rats in the group that got the highest tungsten dose became thinner even than the animals in the control group, despite the fatty diet they were on.
When the researchers measured the rats' body composition, they noticed that tungsten supplementation had reduced the amount of fat reserves. Cells in the fat tissue had even died.
Cells in both muscle tissue [gM] and fat tissue [eWAT] had both started to make more of the proteins UCP2 and UCP3. UCPs, or uncoupling proteins, which boost cells' caloric expenditure.
"These findings strongly support tungstate as an attractive therapeutic approach for the treatment of obesity", the researchers conclude. Sounds promising, but experimenting with tungsten may not be a good idea. Although it’s not very toxic, tungsten doesn't belong in your body. Doses as high as those the Spaniards used will cause problems in the long run.
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