ergo-log.com

Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "

about us

/

contact

/

Ergo-Log

07.10.2011


Ginger, a prostate cancer inhibitor

Nearly all men, if they live long enough, develop prostate cancer. Not a great prospect, which is why there's a great interest in cheap, non-toxic supplements that inhibit prostate cancer. In 2012, researchers at Georgia State University reported that they found a promising one: ginger extract.


Ginger – prostate cancer inhibitor


In vitro study

In 20212, the British Journal of Nutrition published the results of an American study in which ginger [Zingiber officinale] extract killed human prostate cancer cells.

The researchers did test-tube experiments on cells, and observed that more died at concentrations around 100 microgram/millilitre. Healthy prostate cells [PrEC] and human primary fibroblasts [HDT] did not die.

GE = ginger-extract.


Ginger – prostate cancer inhibitor


Animal study
The researchers implanted human PC-3 prostate cancer cells in mice. Some of the mice were given daily oral doses of 100 mg ginger extract per kg bodyweight; others were given nothing. The experiment lasted eight weeks, during which time the extract halved the growth of the tumour.

The human equivalent of this dose – based on a man weighing 70 kg – is 567 mg extract per day.

A hundred grams of fresh ginger will give you this, the researchers have estimated. [We prefer the extract, thank you very much- ed.]


Ginger – prostate cancer inhibitor


The extract inhibited the synthesis of cyclin B1, D1 and E. Cyclines are proteins that direct the development of a cell. Protein synthesis is higher in cancer cells. The extract boosted the concentration of p21 and active caspase-3.

These two proteins are active when cells commit suicide. Cancer cells deactivate these suicide mechanisms, but apparently ginger is capable of reactivating them.

Conclusion
"Our data present the potential usefulness of ginger extract in prostate cancer and warrant further studies", the researchers write.

Source:
Br J Nutr. 2012 Feb;107(4):473-84.

More:
The antiviral effect of fresh ginger 06.04.2021
Susceptible to cold and flu? Natural Care Tea (which contains ginger) boosts your immune system 16.02.2020
Ginger, a natural hay fever medicine 13.06.2020

Archives:
Cancer Prevention & Survival
Prostate Health
Ginger


Eat mushrooms and reduce your risk of prostate cancer Meta-study determines the protective effect of lycopene against prostate cancer Quercetin protects athletes from colds and flu

Eat mushrooms and reduce your risk of prostate cancer
Men who eat mushrooms at least 3 times a week reduce their risk of prostate cancer by 17 percent.

Meta-study determines the protective effect of lycopene against prostate cancer
For years, news media bombarded readers with reports of studies in which lycopene, a compound in tomatoes, protects men against prostate cancer.

An anti-cancer factor in the skin of apples
We recently wrote about an in vitro study in which Pink Lady apple peel extracts inhibited the growth of cancer cells.