Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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30.08.2008 |
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Monster anabolic dimethandrolone does not aromatize
The prospects for the new anabolic steroid dimethandrolone – full name 7-alpha,11-beta-dimethyl-19-nortestosterone – are looking increasingly good. According to researchers at US-based Bioqual, the chance of users being subjected to oestrogenic side-effects is nil. In test-tube experiments dimethandrolone did not convert into oestrogenic compounds.
Yeehaw.
At congresses on male contraceptives, though, researchers have reported contradictory effects on the fertility of experimental animals that were given dimethandrolone. When given low doses, animals become sterile, but apparently not when given high doses. [Science Daily October 1, 2007]
The figure below shows what happened when the researchers added testosterone to the enzyme. The amount of testosterone decreases, and the amount of estradiol increases.
The next graph shows what happened when the researchers repeated the experiment with dimethandrolone instead of testosterone.
Nothing at all. The oestrogen that would have been produced if the aromatase enzyme did get to work on dimethandrolone is 7-alpha,11-beta-dimethyl-estradiol. When the scientists synthesized that oestrogen and tested it in test tubes, they noticed that it interacted ten per cent less well with the alpha- and beta-receptor for estradiol than estradiol itself. If the enzyme had worked, then the oestrogenic effect would still have been considerable.
The researchers repeated the above experiment with MENT or 7-alpha-methyl-19-nortestosterone. MENT was pretty hip for a while in the anabolics scene, and it looked set to enter the market. But when it turned out not to work so well in oral form, whereas the new dimethandrolone can be taken orally, interest waned.
The graph below shows what aromatase does with MENT.
MENT does aromatize – a bit. The oestrogen that is produced, 7-alpha-methyl-estradiol, is a teeny-weeny bit stronger than ordinary estradiol.
When the researchers repeated the experiment again with 11-beta-methyl-19-nortestosterone they discovered that
We know enough.
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