Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
L-Serine supplementation may make the yo-yo effect a thing of the past
Losing weight is difficult, keeping the lost pounds of body fat away after a successful slimming diet is even more difficult. Perhaps L-serine supplementation will make this task a little less impossible, suggests a German animal study published in Nutrients. And perhaps supplementation with L-serine is also very interesting for people who are experimenting with part-time fasting.
Both the HFD and CD groups were then given a portion of drinking water in which the researchers had dissolved the amino acid L-serine. If the mice had been adult humans, they would have received about 10-14 grams of L-serine per day.
In 2019, Chinese researchers published an animal study in which they gave old mice serine for six months, and found that the animals became slimmer as a result. [Front Endocrinol (Lausanne). 2018 Aug 23;9:476.] This was probably because the amino acid reduced the activity of appetite hormones. Incidentally, the Chinese used half the dose with which the Germans experimented.
The Chinese experiments were the impetus for the German study.
Serine supplementation did, however, have a positive effect when the researchers made the mice lose weight by fasting them several times. After the fasting periods, serine reduced body weight gain when the animals were able to eat as much as they wanted.
Hmm... What would happen if you supplemented not only with L-serine but also with L-carnitine during fasting cycles?