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24.05.2018

Intermittent fasting may prevent diabetes type-2

Intermittent fastening makes men, who are on their way to become diabetic, healthier. This is evident from a small human study that researchers from the American Pennington Biomedical Research Center will soon publish in Cell Metabolism. According to that study, intermittent fasting improves insulin sensitivity and blood pressure.

Study
The researchers had 8 men aged 35-70 years, who were in a pre-stage of type-2 diabetes, eating for 5 weeks in a regular way. This meant that the men used 3 meals every day between 8 o'clock in the morning and 8 o'clock in the evening.

On another occasion, the men did intermittent fasting for 5 weeks. They used 3 meals between 8 o'clock in the morning and 12 o'clock in the afternoon.

The researchers had control over the intake of the men. Whether they did part time fasting or ate on the regular maner, they ate exactly the same foods in identical quantities. The men did not lose weight during the intermittent fasting period.

Results
After 5 weeks of intermittent fasting, the men's bodies produced less insulin after glucose administration. Their bodies needed less insulin to make the glucose to disappear from their blood. Intermitttent fasting increased insulin sensitivity.

The amount of triglycerides in the blood increased due to intermittent fasting. On the other hand, intermittent fasting decreased blood pressure.

After 5 weeks of intermittent fasting, the men reported less hunger than after 5 weeks of eating in the regular way.

Conclusion
"We know intermittent fasting improves metabolism and health", says research leader Courtney Peterson in a press release. [uab.edu May 10, 2018] "However, we didn't know whether these effects are simply because people ate less and lost weight."

Peterson and her co-workers suspect that it is important that the subjects ate in the morning, and not in the afternoon and in the evening. Not all athletes and life-extensionist who have already gained practical experience with part-time fastening will agree with them on this.

"Our trial tested early time-restricted feeding in men with prediabetes - a population at great risk of developing diabetes - and indicates that early time-restricted feeding is an efficacious strategy for treating both prediabetes and likely also prehypertension", the researchers write.

"We speculate that early time-restricted feeding - by virtue of combining daily intermittent fasting and eating in alignment with circadian rhythms in metabolism - will prove to be a particularly efficacious form of intermittent fasting."

Source:
Cell Metab. 2018 May 8. pii: S1550-4131(18)30253-5.

More:
Fasting activates stem cells to regenerate tissues 16.05.2018
Why a low-carbohydrate diet might make intermittent fasting more effective 30.03.2018
Experienced strength athletes lose fat by intermittent fasting, not muscle mass or strength 29.03.2017

Archives:
Insulin & Glucose Metabolism
Cardiovascular Health
Intermittent Fasting

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