Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
Beta-AIBA, a new weight-loss supplement
A new slimming supplement has become available recently in online stores and we, the ignoramus compilers of this free webzine, freely admit we are very excited about it. The stuff is called beta-aminoisobutyric acid [beta-AIBA for short], and it works in a different way to all other substances you find in weight-loss supplements.
Beta-AIBA is released by the muscles and then stimulates fat burning in the liver and in fat cells. This is made possible because beta-AIBA transforms white fat cells into fat cells that resemble brown fat cells. The researchers call these white fat cells that have been transformed by beta-AIBA 'beige fat cells'.
White fat cells are the classic fat cells; all they are capable of doing is storing fat. Brown fat cells are fat cells that can convert the fat they have stored into heat. Adults have few brown fat cells left, but the number can be increased by exposure to factors such as cold and some substances that imitate the effects of adrenalin.
The figure below shows that in the fat cells of mice that had been given 100 mg [+] or 170 mg [++] beta-AIBA daily in their drinking water there was an increase in activity of the typical 'brown' fat cell genes such as UCP-1, CIDEA and PGC-1-alpha.
Mice in a control group were given no beta-AIBA. [-]
The animals didn't become more active [below left] or less active [below right].
The decrease in weight was entirely due to an increase in calorie burning.
Watch this space.