Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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17.09.2011 |
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Man's testosterone level sky-high from ActivaTe Xtreme
For the record: Driven Sports recently changed the composition of ActivaTe Xtreme. The supplement we discuss in this article is the 'old' ActivaTe Xtreme. The composition of the product is shown below. It's worth repeating though that pro-hormones and designer steroids are conspicuous by their absence. For a start, the ActivaTe version we're talking about contains 3,4-divanillyltetrahydrofuran, known for short as divanil [structural formula shown below].
ActivaTe Xtreme also contains indole-3-carbinol, aka I3C. This is a compound found in cabbages. I3C stimulates enzymes that convert estradiol into inactive metabolites. Less estradiol means that the pituitary produces more LH. And LH is the hormone that stimulates the testes to produce testosterone.
And last but not least, ActivaTe Xtreme contains good ol' zinc, and extracts of Pinus sylvestris extract and Rhodiola rosea. Zinc supplementation boosts testosterone production – at least it does if you're not scared of high doses.
The man also had abnormally high amounts of estradiol in his blood. That was because testosterone had converted, the doctors suspected. The man was told to keep off the supplement for a month, after which time the doctors examined him again. His blood levels had normalised.
So, according to the doctors, it was the supplement that had caused the man's testosterone level to go through the roof. But why, despite the high testosterone level, the man complained of having a low sex drive is not clear from the article. The doctors don't even mention the issue. They do indicate that they are impressed with the formula of ActivaTe Xtreme.
The stuff was made in the same way as an anti-oestrogen like tamoxifen. It apparently never occurred to the doctors to ask the man if he hadn't been using nolvadex or something similar on the sly, and they didn't look for it in his blood either.
"The development of ActivaTe Xtreme is a very clever piece of biochemical trickery", the Brits write. "This case highlights a novel biochemical pattern that we should be aware of; a raised testosterone that is not associated with a suppressed LH and warrants further investigation."
The latest version of ActivaTe Xtreme no longer contains Basella alba. This extract not only boosts testosterone production, but also that of estradiol. The new version does contain extracts of Brassaiopsis glomerulata, however, and these have an anti-oestrogenic effect.
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