Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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14.03.2009 |
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More damaged livers from methasterone and madol
The Superdrol user was 21. He was nauseous, had stopped eating, had jaundice and itched all over. He'd been using Superdrol for a couple of months and his liver was not functioning properly. His data is shown in the table below, under the heading Patient 1.
When the symptoms had got worse after two weeks, the doctors gave him prednisone. The anti-inflammatory worked and after another six weeks, he'd made a pretty good recovery.
Methasterone, the active compound in Superdrol, is a steroid whose structure and synthesis resemble those of oxymetholone. It was also developed and tested in the late fifties by the makers of oxymetholone, the American pharmaceutical company Syntex. Although methasterone [see structural formula below] looked like a promising anabolic steroid in animal tests, in subsequent tests potential side effects showed up. Syntex decided not to put methasterone on the market. But that didn't stop designer supplement makers from marketing the forgotten steroid years later.
What patient 2 used was not clear, but it contained at least DHEA. Of the three men referred to in the study, number 2 got off the most lightly. He recovered spontaneously a couple of weeks after he had stopped using the supplement.
Not much is known about the side-effects of madol. It is not carcinogenic, say German researchers. But they did discover that it enlarged the heart muscle in animal tests. The enlargement itself was not dangerous, but the researchers were not entirely convinced. In the bodybuilding circuit however there are few stories around of users who have developed liver problems as a result of using madol.
The sick madol user had to be given prednisone in the end, after which he recovered.
BMF Hardcore, the maker of M-Test, has heavier oral designer supplements among its products. The Canadian government has issued warnings about these. Maybe something went wrong during the production of M-Test 2. Or perhaps the doctors got it wrong that Patient 3 used the BMF product.
The doctors also read a couple of articles written by colleagues and summarized the information they found. This resulted in the table you see here below.
Liver specialists should get extra training on designer supplements that contain oral anabolic steroids, the article concludes. "The rapid reporting of several cases of AAS-induced liver injury from dietary supplements emphasizes the growing emergence and importance of this condition and the need for clinicians to become aware of the sequelae of jaundice and renal failure, especially among young men who are unknowingly consuming hepatotoxic agents."
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